2019
Singh DK, Németh T, Papp A, Tóth R, Lukácsi S, Heidingsfeld O, Dostal J, Vágvölgyi C, Bajtay Z, Józsi M, Gácser A (2019). Functional Characterization of Secreted Aspartyl Proteases in Candida parapsilosis. mSphere 4(4). pii: e00484-19.
Llopis-Torregrosa V, Vaz C, Monteoliva L, Ryman K, Engstrom Y, Gacser A, Gil C, Ljungdahl PO, Sychrová H (2019). Trk1-mediated potassium uptake contributes to cell-surface properties and virulence of Candida glabrata. Sci Rep 9(1):7529.
Zamith-Miranda D, Heyman HM, Cleare LG, Couvillion SP, Clair GC, Bredeweg EL, Gacser A, Nimrichter L, Nakayasu ES, Nosanchuk JD (2019). Multi-omics Signature of Candida auris, an Emerging and Multidrug-Resistant Pathogen. mSystems 4(4) pii: e00257-19.
Tóth R, Nosek J, Mora-Montes HM, Gabaldon T, Bliss JM, Nosanchuk JD, Turner SA, Butler G, Vágvölgyi C, Gácser A (2019). Candida parapsilosis: from Genes to the Bedside. Clin Microbiol Rev 32(2). pii: e00111-18.
2018
Papp C, Kocsis K, Tóth R, Bodai L, Willis JR, Ksiezopolska E, Lozoya-Pérez NE, Vágvölgyi C, Mora Montes H, Gabaldón T, Nosanchuk JD, Gácser A (2018). Echinocandin-Induced Microevolution of Candida parapsilosis Influences Virulence and Abiotic Stress Tolerance. mSphere 14;3(6).
Zoppo M, Lombardi L, Rizzato C, Lupetti A, Bottai D, Papp C, Gácser A, Tavanti A (2018). CORT0C04210 is required for Candida orthopsilosis adhesion to human buccal cells. Fungal Genet Biol 120:19-29
Chakraborty T, Thuer E, Heijink M, Tóth R, Bodai L, Vágvölgyi C, Giera M, Gabaldón T, Gácser A (2018). Eicosanoid biosynthesis influences the virulence of Candida parapsilosis. Virulence 9(1):1019-1035.
Tóth R, Cabral V, Thuer E, Bohner F, Németh T, Papp C, Nimrichter L, Molnár G, Vágvölgyi C, Gabaldón T, Nosanchuk JD, Gácser A (2018). Investigation of Candida parapsilosis virulence regulatory factors during host-pathogen interaction. Sci Rep 8(1):1346.
2017
Csonka K, Vadovics M, Marton A, Vágvölgyi C, Zajta E, Tóth A, Tóth R, Vizler C, Tiszlavicz L, Mora-Montes HM, Gácser A (2017). Investigation of OCH1 in the Virulence of Candida parapsilosis Using a New Neonatal Mouse Model. Front Microbiol. 8:1197.
Nagy LG, Toth R, Kiss E, Slot J, Gacser A, Kovacs GM (2017) Six Key Traits of Fungi: Their Evolutionary Origins and Genetic Bases. Microbiol Spectr 5
Cillingova A, Zeman I, Toth R, Nebohacova M, Dunckova I, Holcova M, Jakubkova M, Gerecova G, Pryszcz LP, Tomaska L, Gabaldon T, Gacser A, Nosek J (2017) Eukaryotic transporters for hydroxyderivatives of benzoic acid. Sci Rep 7: 8998
Csonka K, Vadovics M, Marton A, Vagvolgyi C, Zajta E, Toth A, Toth R, Vizler C, Tiszlavicz L, Mora-Montes HM, Gacser A (2017) Investigation of OCH1 in the Virulence of Candida parapsilosis Using a New Neonatal Mouse Model. Front Microbiol 8: 1197
Toth A, Zajta E, Csonka K, Vagvolgyi C, Netea MG, Gacser A (2017) Specific pathways mediating inflammasome activation by Candida parapsilosis. Sci Rep 7: 43129
2016
Berkovits C, Toth A, Szenzenstein J, Deak T, Urban E, Gacser A, Nagy K (2016) Analysis of oral yeast microflora in patients with oral squamous cell carcinoma. Springerplus 5: 1257
Gacser A (2016) Adhesins in Candida parapsilosis: Understudied players in virulence. Virulence 7: 65-67
Gaspar R, Pipicz M, Hawchar F, Kovacs D, Djirackor L, Gorbe A, Varga ZV, Kiricsi M, Petrovski G, Gacser A, Csonka C, Csont T (2016) The cytoprotective effect of biglycan core protein involves Toll-like receptor 4 signaling in cardiomyocytes. J Mol Cell Cardiol 99: 138-150
Mora-Montes HM, Gacser A (2016) Editorial: Recent Advances in the Study of the Host-Fungus Interaction. Front Microbiol 7: 1694
Perez-Garcia LA, Csonka K, Flores-Carreon A, Estrada-Mata E, Mellado-Mojica E, Nemeth T, Lopez-Ramirez LA, Toth R, Lopez MG, Vizler C, Marton A, Toth A, Nosanchuk JD, Gacser A, Mora-Montes HM (2016) Role of Protein Glycosylation in Candida parapsilosis Cell Wall Integrity and Host Interaction. Front Microbiol 7: 306
Toth R, Toth A, Vagvolgyi C, Gacser A (2016) Candida parapsilosis secreted lipase as an important virulence factor. Curr Protein Pept Sci
2015
Pryszcz LP, Nemeth T, Saus E, Ksiezopolska E, Hegedusova E, Nosek J, Wolfe KH, Gacser A, Gabaldon T (2015) The Genomic Aftermath of Hybridization in the Opportunistic Pathogen Candida metapsilosis. PLoS Genet 11: e1005626
Grozer Z, Toth A, Toth R, Kecskemeti A, Vagvolgyi C, Nosanchuk JD, Szekeres A, Gacser A (2015) Candida parapsilosis produces prostaglandins from exogenous arachidonic acid and OLE2 is not required for their synthesis. Virulence 6: 85-92
Toth R, Alonso MF, Bain JM, Vagvolgyi C, Erwig LP, Gacser A (2015) Different Candida parapsilosis clinical isolates and lipase deficient strain trigger an altered cellular immune response. Front Microbiol 6: 1102
Estrada-Mata E, Navarro-Arias MJ, Perez-Garcia LA, Mellado-Mojica E, Lopez MG, Csonka K, Gacser A, Mora-Montes HM (2015) Members of the Candida parapsilosis Complex and Candida albicans are Differentially Recognized by Human Peripheral Blood Mononuclear Cells. Front Microbiol 6: 1527
2014
Toth R, Toth A, Papp C, Jankovics F, Vagvolgyi C, Alonso MF, Bain JM, Erwig LP, Gacser A (2014) Kinetic studies of Candida parapsilosis phagocytosis by macrophages and detection of intracellular survival mechanisms. Front Microbiol 5: 633
Nagy LG, Ohm RA, Kovacs GM, Floudas D, Riley R, Gacser A, Sipiczki M, Davis JM, Doty SL, de Hoog GS, Lang BF, Spatafora JW, Martin FM, Grigoriev IV, Hibbett DS (2014) Latent homology and convergent regulatory evolution underlies the repeated emergence of yeasts. Nat Commun 5: 4471
Holland LM, Schroder MS, Turner SA, Taff H, Andes D, Grozer Z, Gacser A, Ames L, Haynes K, Higgins DG, Butler G (2014) Comparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans. PLoS Pathog 10: e1004365
Pryszcz LP, Nemeth T, Gacser A, Gabaldon T (2014) Genome comparison of Candida orthopsilosis clinical strains reveals the existence of hybrids between two distinct subspecies. Genome Biol Evol 6: 1069-1078
Pallagi P, Balla Z, Singh AK, Dosa S, Ivanyi B, Kukor Z, Toth A, Riederer B, Liu Y, Engelhardt R, Jarmay K, Szabo A, Janovszky A, Perides G, Venglovecz V, Maleth J, Wittmann T, Takacs T, Gray MA, Gacser A, Hegyi P, Seidler U, Rakonczay Z, Jr. (2014) The role of pancreatic ductal secretion in protection against acute pancreatitis in mice*. Crit Care Med 42: e177-188
Singaravelu K, Gacser A, Nosanchuk JD (2014) Genetic determinants of virulence – Candida parapsilosis. Rev Iberoam Micol 31: 16-21
Gacser A, Tiszlavicz Z, Nemeth T, Seprenyi G, Mandi Y (2014) Induction of human defensins by intestinal Caco-2 cells after interactions with opportunistic Candida species. Microbes Infect 16: 80-85
2013
Toth A, Csonka K, Jacobs C, Vagvolgyi C, Nosanchuk JD, Netea MG, Gacser A (2013) Candida albicans and Candida parapsilosis induce different T-cell responses in human peripheral blood mononuclear cells. J Infect Dis 208: 690-698
Pryszcz LP, Nemeth T, Gacser A, Gabaldon T (2013) Unexpected genomic variability in clinical and environmental strains of the pathogenic yeast Candida parapsilosis. Genome Biol Evol 5: 2382-2392
Nemeth T, Toth A, Szenzenstein J, Horvath P, Nosanchuk JD, Grozer Z, Toth R, Papp C, Hamari Z, Vagvolgyi C, Gacser A (2013) Characterization of virulence properties in the C. parapsilosis sensu lato species. PLoS One 8: e68704
Connolly LA, Riccombeni A, Grozer Z, Holland LM, Lynch DB, Andes DR, Gacser A, Butler G (2013) The APSES transcription factor Efg1 is a global regulator that controls morphogenesis and biofilm formation in Candida parapsilosis. Mol Microbiol 90: 36-53
Szenzenstein J, Gacser A, Grozer Z, Farkas Z, Nagy K, Vagvolgyi C, Marki-Zay J, Pfeiffer I (2013) Differential sensitivity of the species of Candida parapsilosis sensu lato complex against statins. Mycopathologia 176: 211-217
Pammi M, Holland L, Butler G, Gacser A, Bliss JM (2013) Candida parapsilosis is a significant neonatal pathogen: a systematic review and meta-analysis. Pediatr Infect Dis J 32: e206-216
2012
Valach M, Pryszcz LP, Tomaska L, Gacser A, Gabaldon T, Nosek J (2012) Mitochondrial genome variability within the Candida parapsilosis species complex. Mitochondrion 12: 514-519
Voigt CA, Schafer W, Salomon S (2005) A secreted lipase of Fusarium graminearum is a virulence factor required for infection of cereals. Plant J 42: 364-375
Horvath P, Nosanchuk JD, Hamari Z, Vagvolgyi C, Gacser A (2012) The identification of gene duplication and the role of secreted aspartyl proteinase 1 in Candida parapsilosis virulence. J Infect Dis 205: 923-933
2011
Nguyen LN, Gacser A, Nosanchuk JD (2011a) Secreted lipases supply fatty acids for yeast growth in the absence of de novo fatty acid synthesis. Virulence 2: 538-541
Nguyen LN, Gacser A, Nosanchuk JD (2011b) The stearoyl-coenzyme A desaturase 1 is essential for virulence and membrane stress in Candida parapsilosis through unsaturated fatty acid production. Infect Immun 79: 136-145
Nguyen LN, Hamari Z, Kadereit B, Trofa D, Agovino M, Martinez LR, Gacser A, Silver DL, Nosanchuk JD (2011c) Candida parapsilosis fat storage-inducing transmembrane (FIT) protein 2 regulates lipid droplet formation and impacts virulence. Microbes Infect 13: 663-672
2009
Trofa D, Agovino M, Stehr F, Schafer W, Rykunov D, Fiser A, Hamari Z, Nosanchuk JD, Gacser A (2009) Acetylsalicylic acid (aspirin) reduces damage to reconstituted human tissues infected with Candida species by inhibiting extracellular fungal lipases. Microbes Infect 11: 1131-1139
Nosek J, Holesova Z, Kosa P, Gacser A, Tomaska L (2009) Biology and genetics of the pathogenic yeast Candida parapsilosis. Curr Genet 55: 497-509
Martinez LR, Mihu MR, Gacser A, Santambrogio L, Nosanchuk JD (2009) Methamphetamine enhances histoplasmosis by immunosuppression of the host. J Infect Dis 200: 131-141
2008
Trofa D, Gacser A, Nosanchuk JD (2008) Candida parapsilosis, an emerging fungal pathogen. Clin Microbiol Rev 21: 606-625
Talloczy Z, Martinez J, Joset D, Ray Y, Gacser A, Toussi S, Mizushima N, Nosanchuk JD, Goldstein H, Loike J, Sulzer D, Santambrogio L (2008) Methamphetamine inhibits antigen processing, presentation, and phagocytosis. PLoS Pathog 4: e28
Shi L, Albuquerque PC, Lazar-Molnar E, Wang X, Santambrogio L, Gacser A, Nosanchuk JD (2008) A monoclonal antibody to Histoplasma capsulatum alters the intracellular fate of the fungus in murine macrophages. Eukaryot Cell 7: 1109-1117
Nosanchuk JD, Gacser A (2008) Histoplasma capsulatum at the host-pathogen interface. Microbes Infect 10: 973-977
Lazar-Molnar E, Gacser A, Freeman GJ, Almo SC, Nathenson SG, Nosanchuk JD (2008) The PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum. Proc Natl Acad Sci U S A 105: 2658-2663
2007
Martinez LR, Ntiamoah P, Gacser A, Casadevall A, Nosanchuk JD (2007) Voriconazole inhibits melanization in Cryptococcus neoformans. Antimicrob Agents Chemother 51: 4396-4400
Gacser A, Schafer W, Nosanchuk JS, Salomon S, Nosanchuk JD (2007a) Virulence of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis in reconstituted human tissue models. Fungal Genet Biol 44: 1336-1341
Gacser A, Stehr F, Kroger C, Kredics L, Schafer W, Nosanchuk JD (2007b) Lipase 8 affects the pathogenesis of Candida albicans. Infect Immun 75: 4710-4718
Gacser A, Trofa D, Schafer W, Nosanchuk JD (2007c) Targeted gene deletion in Candida parapsilosis demonstrates the role of secreted lipase in virulence. J Clin Invest 117: 3049-3058
2005
Gacser A, Salomon S, Schafer W (2005) Direct transformation of a clinical isolate of Candida parapsilosis using a dominant selection marker. FEMS Microbiol Lett 245: 117-121
