Project title : Resistance mechanisms and their impact in Candida parapsilosis.

Fungal infections are emerging world wide. The leader causes of these diseases are Candida species. Treatment against Candida species are performed using azoles, echinocandins and amphotericin B. For these microorganisms it is essential to evolve resistance against the most commonly used antimycotics. However, many studies have showed the fitness and virulence cost of drug resistant Candida strains. My work is focusing on the mechanisms of resistance development and their influence on virulence and fitness.